If you are working with a model that has -NT or -NT2 in the end of the model number, for example RDR-80581AGU-NT2-20, you will need to install the NT-Ware driver.
First you will want to download the rf IDEAS Configuration Utility found here.
Once you have the utility open, in the lower right corner click on the plus icon. Then select the Install libusb for NTWCC reader option.
Follow the installer prompts and you are all done. Now you should be able to connect to the configuration utility.